Investigating how modifiable risk factors affect midlife cognition in diverse populations
Modifiable risk factors and midlife cognition in diverse populations: a pooled cohort study
['FUNDING_CAREER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10887288
This study is looking at how certain lifestyle choices and health factors can affect memory and thinking skills as people reach middle age, especially in different racial and ethnic groups, to help find ways to prevent Alzheimer's and related conditions.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10887288 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how modifiable risk factors influence cognitive decline during midlife, particularly among diverse racial and ethnic groups. It aims to identify high-risk individuals and explore the mechanisms behind cognitive disparities related to Alzheimer's Disease and related dementias. By analyzing data from three longitudinal cohort studies, the research seeks to uncover the impact of these risk factors on cognitive health and the underlying biological pathways involved. The goal is to inform prevention strategies that can be tailored to diverse populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 40-65 years, particularly those from diverse racial and ethnic backgrounds who may be at risk for cognitive decline.
Not a fit: Patients outside the age range of 40-65 years or those not at risk for cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for cognitive decline in midlife, particularly for underrepresented populations.
How similar studies have performed: Previous research has shown success in identifying modifiable risk factors for cognitive decline, making this approach both relevant and promising.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JIANG, XIAQING — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: JIANG, XIAQING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer disease prevention