Investigating how mitochondrial factors contribute to liver cancer disparities in Hispanics
Official title: The mitochondrial aspects of health disparity of hepatocellular carcinoma in Hispanic population
Funded at University of Texas Hlth Science Center · NIH-11064597 · Data updated 2026-11-12
This study is looking into why liver cancer is more common in Hispanic people in South Texas, focusing on how certain genetic factors and Hepatitis C might play a role, and it hopes to find ways to improve prevention and treatment for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $66,936 |
| NIH project number | 3R01CA283840-01S1 |
| Project ID | NIH-11064597 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Hispanic individuals at risk for hepatocellular carcinoma, particularly those with Hepatitis C Virus infection or other liver health issues.
✕Less likely to help
Patients who are not of Hispanic descent or those without risk factors for liver disease may not benefit from this research.
What this research studies
This research focuses on understanding the reasons behind the higher rates of hepatocellular carcinoma (HCC) in the Hispanic population, particularly in South Texas. It examines the role of mitochondrial DNA variations and dysfunction, alongside the impact of Hepatitis C Virus (HCV) infection, in the development of HCC. By analyzing genetic factors and their relationship with liver health, the study aims to uncover insights that could lead to better prevention and treatment strategies for affected individuals. Patients may be involved in providing biological samples or health data to support this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and targeted interventions for liver cancer in Hispanic patients.
How similar studies have gone: Previous research has shown that genetic factors, including mitochondrial variations, can influence cancer risk, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Bai, Yidong — University of Texas Hlth Science Center
- Study coordinator: Bai, Yidong
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.