Investigating how mitochondria affect heart health in diabetes
Molecular Regulators of Mitochondria in Diabetic Cardiomyopathy
This study is looking at how tiny parts of your cells, called mitochondria and membranes, affect heart health in people with diabetes, and it hopes to find new ways to help improve heart function for those living with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-11098486 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of mitochondria and cell membranes in heart disease related to diabetes. It aims to identify molecular regulators that could help improve cardiac function in diabetic patients by studying how these regulators interact with signaling pathways. The approach involves examining the changes in mitochondrial function and membrane structure that occur in diabetes, which may lead to new therapeutic targets. By merging findings from previous studies on caveolin biology and ischemia-reperfusion injury, the research seeks to uncover novel mechanisms that could protect the heart from diabetic stress.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with adult-onset diabetes who are experiencing cardiac dysfunction.
Not a fit: Patients without diabetes or those with non-cardiac related complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart health and reduce the risk of heart disease in diabetic patients.
How similar studies have performed: Previous research has shown promising results in understanding the role of mitochondrial function in heart disease, indicating that this approach could yield valuable insights.
Where this research is happening
San Diego, United States
- VA San Diego Healthcare System — San Diego, United States (Active)
Researchers
- Principal investigator: Patel, Hemal H — VA San Diego Healthcare System
- Study coordinator: Patel, Hemal H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.