NIH-funded research NIH-funded research

Investigating how mindfulness therapy affects emotional control in people with depression

Official title: Affective Executive Functioning as a Mechanism of Mindfulness-Based Cognitive Therapy: A Pilot Randomized Controlled Trial

Funded at Butler Hospital (Providence, Ri) · NIH-10995316 · Data updated 2026-11-12

This study is looking at how an 8-week Mindfulness-Based Cognitive Therapy program can help adults with depression manage their emotions better, and you'll be comparing it to a health education class to see which one works best.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionButler Hospital (Providence, Ri)
NIH-funded
Lab location1 site (Providence, United States)
Project startJanuary 1, 2022
Project endDecember 31, 2026
Funding year2025
Award (this year)$176,903
NIH project number5K23AT011388-04
Project IDNIH-10995316 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who are experiencing symptoms of depression.

Less likely to help

Patients who do not have symptoms of depression or are under 21 years old may not benefit from this research.

What this research studies

This research explores the effects of Mindfulness-Based Cognitive Therapy (MBCT) on emotional regulation in adults experiencing symptoms of depression. Participants will be randomly assigned to either an 8-week MBCT program or a health education class, allowing researchers to compare the outcomes of these two approaches. Throughout the study, participants will complete various computer-based tasks to assess their emotional control at multiple points during the program. The goal is to better understand how MBCT influences cognitive processes related to emotional functioning and depression.

Why it matters

Potential benefit: If successful, this research could lead to improved therapeutic strategies for managing depression by enhancing emotional regulation.

How similar studies have gone: Previous research has shown that mindfulness-based therapies can be effective for depression, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Butler Hospital (Providence, Ri)
    Providence, United States
    Active

Researchers

  • Principal investigator: Kraines, Morganne a — Butler Hospital (Providence, Ri)
  • Study coordinator: Kraines, Morganne a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.