Investigating how mindfulness and slow breathing affect brain responses

fMRI of cerebral responses to breathing of mindfulness and slow paced breathing at brainstem and higher brain

NIH-funded research Massachusetts General Hospital · NIH-11070409

This study is looking at how paying attention to your breathing can change how your brain works, and it's for anyone interested in how mindfulness might help improve their mental and physical health.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11070409 on NIH RePORTER

What this research studies

This research focuses on understanding how mindfulness, particularly through attention to breathing, influences brain activity. Using functional magnetic resonance imaging (fMRI), the study will map brain responses to different breathing patterns, including mindfulness-based breathing and slow-paced breathing. By examining the brain's responses at both the brainstem and higher brain regions, the research aims to uncover the connections between breathing patterns and brain function. This could provide insights into how mindfulness practices can affect mental and physical health.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals interested in mindfulness practices or those experiencing stress and anxiety.

Not a fit: Patients who do not engage in mindfulness or breathing exercises may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance mindfulness practices, leading to improved mental health and well-being for patients.

How similar studies have performed: Previous research has shown promising results in understanding the brain's response to mindfulness and breathing techniques, indicating that this approach is supported by existing evidence.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.