Investigating how microRNAs influence brain cell development
Beyond Transcription - microRNA Regulation of Neuronal Development
['FUNDING_R01'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-11060000
This study is looking at how tiny molecules called microRNAs help brain cells grow and develop, which could give us important clues about conditions like autism and how to better understand them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11060000 on ClinicalTrials.gov |
What this research studies
This research explores the role of microRNAs in the development of neuronal cells, which are crucial for proper brain function. By utilizing advanced techniques in transcriptomics, the study aims to map the developmental pathways of different neuronal subtypes and understand how microRNAs regulate gene expression during these processes. The researchers will implement novel strategies to identify the molecular mechanisms behind these regulatory functions, which could lead to insights into neurodevelopmental disorders. Patients may benefit from a better understanding of how disruptions in these processes contribute to conditions like autism.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder or related neurodevelopmental conditions.
Not a fit: Patients with neurodevelopmental disorders not related to microRNA regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for neurodevelopmental disorders such as autism.
How similar studies have performed: Previous research has shown promising results in understanding the role of microRNAs in brain development, suggesting that this approach could yield significant insights.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIPPI, GIORDANO — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: LIPPI, GIORDANO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder