Investigating how microfluidics can help understand and treat platelet dysfunction in traumatic bleeding.
Using Microfluidics to Identify Mechanisms of Platelet Dysfunction and Assess Therapeutic Efficacy in Traumatic Hemorrhage
This study is looking at how platelets, which help your blood clot, work during serious injuries, and it aims to find better treatments to help people stop bleeding and recover faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11010801 on NIH RePORTER |
What this research studies
This research focuses on using advanced microfluidic technology to explore the mechanisms behind platelet dysfunction, particularly in patients experiencing traumatic hemorrhage. By analyzing blood samples in a controlled environment, the study aims to assess the effectiveness of various therapeutic interventions designed to improve blood clotting and reduce mortality rates. Patients may benefit from insights gained into how their platelets function during trauma, potentially leading to better treatment options. The research will also involve collaboration with multiple departments and institutions to enhance the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced trauma resulting in significant blood loss or hemorrhage.
Not a fit: Patients with non-traumatic causes of bleeding or those who do not have platelet dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from traumatic bleeding, ultimately reducing mortality rates.
How similar studies have performed: Previous research has shown promise in using microfluidics for analyzing blood components, suggesting that this approach could yield valuable insights into platelet dysfunction.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Shea, Susan Marguerite — University of Pittsburgh at Pittsburgh
- Study coordinator: Shea, Susan Marguerite
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.