Investigating how MFAP5 affects skin scar formation
Official title: MFAP5 and Skin Scar Formation
Funded at University of Illinois at Chicago · NIH-11070206 · Data updated 2026-11-12
This study is looking at how certain cells in your body help heal wounds and form scars, focusing on a specific protein that might change how these cells work, with the hope of finding better ways to treat scars and improve healing for everyone.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | May 2, 2023 |
| Project end | May 1, 2027 |
| Funding year | 2025 |
| Award (this year) | $54,538 |
| NIH project number | 5F31AR082287-03 |
| Project ID | NIH-11070206 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have experienced significant skin injuries or surgeries that may result in scarring.
✕Less likely to help
Patients with non-skin related conditions or those who do not have issues with scar formation may not benefit from this research.
What this research studies
This research focuses on understanding the mechanisms behind scar formation, particularly how fibroblasts (cells involved in wound healing) contribute to the development of fibrous scars. The study will explore the role of microfibril-associated protein 5 (MFAP5) in fibroblast activation and its impact on the healing process. By utilizing advanced bioinformatics and laboratory techniques, the research aims to uncover how these cells behave during wound repair and how they might be manipulated to improve healing outcomes. Patients may benefit from insights that could lead to better treatments for scars and fibrosis.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for scar formation and related conditions, enhancing healing and reducing fibrosis.
How similar studies have gone: Previous studies have shown promising results in understanding fibroblast behavior in wound healing, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Han, Chen — University of Illinois at Chicago
- Study coordinator: Han, Chen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.