Investigating how metals in proteins affect cell function
Molecular probes for cellular investigation of metalloenzymes
['FUNDING_OTHER'] · UNIVERSITY OF TEXAS AT AUSTIN · NIH-10842947
This study is looking at how important metals in our bodies help proteins work properly, and it aims to find out how changes in these metals can affect our health, especially for people dealing with conditions related to metal imbalances.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS AT AUSTIN (nih funded) |
| Locations | 1 site (AUSTIN, UNITED STATES) |
| Trial ID | NIH-10842947 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of metals as essential nutrients in cellular processes. It examines how the availability of metal ions influences the state of metalloproteins, which are proteins that contain metal ions and play critical roles in various biological functions. By using advanced molecular probes, the research aims to explore how changes in metal ion levels can affect cellular health and function, particularly in relation to diseases caused by metal imbalances. Patients may benefit from insights gained into how to better manage conditions related to metal homeostasis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to metal deficiencies or toxicities, such as certain metabolic disorders.
Not a fit: Patients with conditions unrelated to metal ion homeostasis or those who do not have any metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for diseases associated with metal imbalances in the body.
How similar studies have performed: Other research has shown promising results in understanding the role of metalloproteins in cellular function, indicating that this approach has potential for significant advancements.
Where this research is happening
AUSTIN, UNITED STATES
- UNIVERSITY OF TEXAS AT AUSTIN — AUSTIN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: QUE, EMILY L — UNIVERSITY OF TEXAS AT AUSTIN
- Study coordinator: QUE, EMILY L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.