Investigating how metals exposure affects brain development and autism in children
Metals Dysregulation, Brain Development, and Autism Spectrum Disorder
This study is looking at how being around certain metals during pregnancy and early childhood might affect brain development and the chances of developing autism, especially in babies who are at higher risk, by checking their baby teeth for clues about metal exposure.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10757317 on NIH RePORTER |
What this research studies
This research examines the impact of exposure to metals during pregnancy and early childhood on brain development and the risk of autism spectrum disorder (ASD). By analyzing the developmental changes in infants, particularly those at higher risk for ASD, the study aims to understand how environmental factors influence cognitive and adaptive functions. Researchers will utilize innovative methods to assess metals exposure through the analysis of shed deciduous teeth, allowing for a detailed understanding of exposure timing and intensity. The findings could provide insights into the relationship between environmental toxins and neurodevelopmental outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include infants and young children, particularly those with a family history of autism or neurodevelopmental delays.
Not a fit: Patients who are older than 11 years or do not have a familial risk of autism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for autism spectrum disorder in children.
How similar studies have performed: Previous research has shown promising results in understanding the effects of environmental exposures on neurodevelopment, making this approach both relevant and potentially impactful.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Volk, Heather E — Johns Hopkins University
- Study coordinator: Volk, Heather E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.