Investigating how metabolism in breast cancer affects tumor behavior
Tumor Microenvironment Metabolism in Invasive Ductal Carcinoma of the Breast
This study is looking at how changes in the way breast cancer cells use energy can make the cancer more aggressive, and it hopes to find new ways to predict outcomes and improve treatments for people with invasive ductal carcinoma.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10881345 on NIH RePORTER |
What this research studies
This research explores the metabolic changes in invasive ductal carcinoma (IDC) of the breast and how these changes contribute to the aggressiveness of the cancer. It focuses on the role of inflammation and oxidative stress in altering the metabolism of tumor cells, particularly how they utilize different metabolic pathways. By understanding these metabolic interactions within the tumor microenvironment, the research aims to identify potential new biomarkers for prognosis and treatment strategies targeting tumor metabolism.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with invasive ductal carcinoma of the breast.
Not a fit: Patients with non-invasive breast cancer or other types of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options and better prognostic tools for patients with invasive ductal carcinoma.
How similar studies have performed: Other research has shown promising results in targeting tumor metabolism, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Martinez Outschoorn, Ubaldo — Thomas Jefferson University
- Study coordinator: Martinez Outschoorn, Ubaldo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.