Investigating how metabolism and energy balance work in mice.
Official title: Mouse Metabolic Physiology Core
Funded at Vanderbilt University · NIH-11017606 · Data updated 2026-11-12
This study looks at how genes and the environment affect insulin and metabolism in mice, helping researchers learn more about weight and behavior, which could lead to better treatments for metabolic disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $226,054 |
| NIH project number | 5U2CDK135073-03 |
| Project ID | NIH-11017606 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with metabolic disorders or those interested in the genetic and environmental factors affecting metabolism.
✕Less likely to help
Patients without metabolic disorders or those not interested in the underlying mechanisms of metabolism may not benefit from this research.
What this research studies
The Mouse Metabolic Physiology Core focuses on understanding the genetic and environmental factors that influence insulin action, metabolism, and energy balance in mice. This research utilizes advanced techniques to perform complex procedures, including surgeries and metabolic analyses, to study how these factors affect body weight and behavior. By examining healthy mice and those with metabolic diseases, the core aims to provide insights that could inform future treatments for metabolic disorders. The experienced team offers critical services to researchers, enhancing the understanding of metabolic physiology.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing metabolic diseases in humans.
How similar studies have gone: Previous research has shown success in using similar methodologies to study metabolic diseases in animal models.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Mcguinness, Owen P — Vanderbilt University
- Study coordinator: Mcguinness, Owen P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.