Investigating how metabolism affects blood vessel growth in heart disease
Official title: Metabolic Control of Epigenetic Reprogramming in Neovascularization
Funded at Texas A&m University Health Science Ctr · NIH-11018630 · Data updated 2026-11-12
This study is looking at how changes in our body's metabolism can help create new blood vessels, which is important for people with heart disease, and it hopes to find new ways to improve blood flow and heart function.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University Health Science Ctr NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project start | February 1, 2023 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $40,688 |
| NIH project number | 5F30HL167457-03 |
| Project ID | NIH-11018630 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with cardiovascular diseases, particularly those experiencing issues related to blood flow and heart function.
✕Less likely to help
Patients with non-cardiovascular conditions or those without significant blood flow issues may not benefit from this research.
What this research studies
This research explores the role of metabolic processes in the formation of new blood vessels, particularly in the context of heart disease. By studying how certain cellular modifications influence the ability of cells to transform and adapt, the research aims to uncover new therapeutic strategies for improving blood flow and restoring heart function. The approach involves examining the effects of specific metabolites on the behavior of endothelial cells, which are crucial for blood vessel formation. Patients may benefit from insights that could lead to innovative treatments for cardiovascular conditions.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance blood vessel growth and improve heart function in patients with cardiovascular diseases.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between metabolism and blood vessel growth, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Texas A&m University Health Science Ctr
College Station, United States Active
Researchers
- Principal investigator: Lu, Alexander J. — Texas A&m University Health Science Ctr
- Study coordinator: Lu, Alexander J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.