Investigating how metabolic tissues communicate to regulate blood sugar and fat levels
Chemical interrogation of metabolic tissue crosstalk
This study is looking at how different parts of the body talk to each other to keep blood sugar and fat levels in check, which is important for people with obesity and diabetes, and it aims to find new proteins that could help develop better treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10878810 on NIH RePORTER |
What this research studies
This research focuses on understanding the communication between different metabolic tissues in the body that helps maintain balanced blood sugar and fat levels. By using innovative chemical methods, the researchers aim to directly measure the proteins secreted by these tissues in living animals, rather than relying on indirect predictions. This approach could uncover new proteins and signaling pathways that play a role in conditions like obesity and diabetes, potentially leading to new treatment options. The study emphasizes the importance of these secreted proteins in regulating metabolism and aims to characterize them more thoroughly.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by adult-onset diabetes or related metabolic disorders.
Not a fit: Patients with non-metabolic conditions or those not affected by diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new therapeutic targets for treating obesity and diabetes.
How similar studies have performed: Other research has shown promise in similar approaches, but this specific methodology is relatively novel.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Long, Jonathan Z — Stanford University
- Study coordinator: Long, Jonathan Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.