Investigating how metabolic changes affect wound healing in diabetic veterans
Metabolic Immunomodulation of Wound-Associated Macrophage Functional Plasticity as a Novel Diagnostic Target in Diabetic Veterans
This study is looking at how diabetes affects wound healing in veterans, especially those at risk of losing a limb, by exploring how certain immune cells work in the healing process and finding ways to better predict and improve their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boise VA Medical Center NIH-funded |
| Lab location | 1 site (Boise, United States) |
| Project ID | NIH-11098487 on NIH RePORTER |
What this research studies
This research focuses on understanding how metabolic factors influence the healing of wounds in diabetic veterans, particularly those who may be at risk for lower limb amputations. The study examines the role of macrophages, a type of immune cell, in the healing process and how their function changes in the presence of diabetes. By analyzing the metabolic environment of wounds, researchers aim to identify potential biomarkers that could help predict healing outcomes and improve treatment strategies for veterans with diabetic ulcers.
Who could benefit from this research
Good fit: Ideal candidates for this research are military veterans with diabetes who are experiencing or at risk for diabetic ulcers.
Not a fit: Patients without diabetes or those who do not have wounds related to diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved healing strategies for diabetic veterans, potentially reducing the incidence of amputations and enhancing their quality of life.
How similar studies have performed: Previous research has shown that understanding the immune response in wound healing can lead to significant advancements in treatment, suggesting that this approach has potential for success.
Where this research is happening
Boise, United States
- Boise VA Medical Center — Boise, United States (Active)
Researchers
- Principal investigator: Ammons, Mary Cloud Bosworth — Boise VA Medical Center
- Study coordinator: Ammons, Mary Cloud Bosworth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.