Investigating how metabolic aging affects older adults
Mid-Career Research and Mentorship in Metabolic Aging
This study is looking at how changes in sugar and fat processing in the body affect the health of older adults, especially those 65 and up, to see how these changes might relate to heart disease, diabetes, and memory problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10840342 on NIH RePORTER |
What this research studies
This research focuses on understanding how changes in glucose and lipid metabolism contribute to health issues in older adults, particularly those aged 65 and older. It examines the role of non-esterified fatty acids (NEFAs) in metabolic aging and their potential impact on conditions like cardiovascular disease, diabetes, and cognitive decline. The research utilizes data from large cohort studies, including the Cardiovascular Health Study and the Ginkgo Evaluation of Memory Study, to analyze metabolic factors and their effects on health outcomes in older populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above, particularly those experiencing metabolic issues or cognitive decline.
Not a fit: Patients under the age of 65 or those without metabolic or cognitive concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing and preventing age-related metabolic disorders and cognitive decline in older adults.
How similar studies have performed: Previous research has shown promising results in understanding metabolic aging and its effects on health, indicating that this approach has potential for significant findings.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Mukamal, Kenneth Jay — Beth Israel Deaconess Medical Center
- Study coordinator: Mukamal, Kenneth Jay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.