Investigating how menthol cigarette smoking affects blood metabolites and lung cancer risk

Menthol cigarette smoking-related blood metabolites and lung cancer risk

NIH-funded research University of Florida · NIH-10833699

This study is looking at how smoking menthol cigarettes might affect the risk of lung cancer, especially in African Americans, by analyzing blood samples to find out what changes in the body could be linked to this type of smoking and cancer.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-10833699 on NIH RePORTER

What this research studies

This research aims to understand the relationship between menthol cigarette smoking and lung cancer risk, particularly among African Americans who are disproportionately affected by this disease. By using a multi-stage metabolomics approach, the study will analyze blood samples to identify specific metabolites linked to menthol smoking and their potential role in lung cancer development. This innovative methodology seeks to uncover hidden factors contributing to lung cancer disparities, providing a more comprehensive understanding of the issue.

Who could benefit from this research

Good fit: Ideal candidates for this research are African American individuals who smoke menthol cigarettes and are at risk for lung cancer.

Not a fit: Patients who do not smoke menthol cigarettes or who are not at risk for lung cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies and targeted interventions for lung cancer among menthol cigarette smokers.

How similar studies have performed: While there have been studies on smoking and lung cancer, this specific approach focusing on menthol cigarette metabolites is novel and has not been extensively tested.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.