Investigating how menthol cigarette smoking affects blood metabolites and lung cancer risk
Official title: Menthol cigarette smoking-related blood metabolites and lung cancer risk
Funded at University of Florida · NIH-10833699 · Data updated 2026-11-12
This study is looking at how smoking menthol cigarettes might affect the risk of lung cancer, especially in African Americans, by analyzing blood samples to find out what changes in the body could be linked to this type of smoking and cancer.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $84,859 |
| NIH project number | 5R03CA273625-02 |
| Project ID | NIH-10833699 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American individuals who smoke menthol cigarettes and are at risk for lung cancer.
✕Less likely to help
Patients who do not smoke menthol cigarettes or who are not at risk for lung cancer may not benefit from this research.
What this research studies
This research aims to understand the relationship between menthol cigarette smoking and lung cancer risk, particularly among African Americans who are disproportionately affected by this disease. By using a multi-stage metabolomics approach, the study will analyze blood samples to identify specific metabolites linked to menthol smoking and their potential role in lung cancer development. This innovative methodology seeks to uncover hidden factors contributing to lung cancer disparities, providing a more comprehensive understanding of the issue.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and targeted interventions for lung cancer among menthol cigarette smokers.
How similar studies have gone: While there have been studies on smoking and lung cancer, this specific approach focusing on menthol cigarette metabolites is novel and has not been extensively tested.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Yoon, Hyung-Suk — University of Florida
- Study coordinator: Yoon, Hyung-Suk
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.