Investigating how menthol affects dependence and health outcomes in e-cigarette users

The effect of menthol on ENDS users' dependence, respiratory, and toxicants emission outcomes

NIH-funded research Florida International University · NIH-11057694

This study is looking at how menthol flavoring in e-cigarettes affects young adults aged 21-35, by observing their smoking habits and health risks in a lab setting, to help understand the impact of menthol on addiction and health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFlorida International University NIH-funded
Lab location1 site (Miami, United States)
Project IDNIH-11057694 on NIH RePORTER

What this research studies

This research examines the impact of menthol flavoring on users of electronic nicotine delivery systems (ENDS), particularly focusing on young adults aged 21-35. The study will involve a clinical lab setting where participants will use ENDS with either menthol or tobacco flavors in a controlled environment. By analyzing puffing patterns, dependence levels, and exposure to harmful substances, the research aims to fill critical gaps in understanding how menthol influences health outcomes and addiction. The findings could inform regulatory standards to mitigate the risks associated with ENDS use.

Who could benefit from this research

Good fit: Ideal candidates for this research are current or recent users of e-cigarettes aged 21 to 35 who are willing to participate in clinical lab sessions.

Not a fit: Patients who do not use e-cigarettes or are outside the age range of 21-35 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better regulations that reduce the health risks associated with menthol-flavored e-cigarettes.

How similar studies have performed: While the effects of flavoring on e-cigarette use have been studied, this specific focus on menthol's impact on dependence and health outcomes is relatively novel.

Where this research is happening

Miami, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.