Investigating how menstrual cycle symptoms relate to lung disease in women with LAM
Menstrual Cycle-Related Symptom Variability as a Prognostic Indicator in Lymphangioleiomyomatosis
This study is looking at how changes in menstrual cycle symptoms might help doctors understand the health of women with Lymphangioleiomyomatosis (LAM) and figure out who might benefit from hormone treatments, so they can offer more personalized care.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10669246 on NIH RePORTER |
What this research studies
This research focuses on understanding how variations in menstrual cycle-related symptoms can serve as indicators for the prognosis of Lymphangioleiomyomatosis (LAM), a rare lung disease that predominantly affects women. The study aims to identify which patients may benefit from hormonal therapies by analyzing their symptoms in relation to their lung function and overall health. By gathering data through surveys and clinical assessments, the research seeks to provide insights that could lead to more personalized treatment options for women suffering from LAM.
Who could benefit from this research
Good fit: Ideal candidates for this research are premenopausal women diagnosed with Lymphangioleiomyomatosis who experience variability in menstrual cycle-related symptoms.
Not a fit: Patients who are postmenopausal or those who do not have Lymphangioleiomyomatosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for women with LAM, potentially enhancing their quality of life and lung function.
How similar studies have performed: Previous studies have indicated the importance of hormonal influences in LAM, but this specific approach to identifying patient subsets for hormonal therapy is novel.
Where this research is happening
Cincinnati, United States
- University of Cincinnati — Cincinnati, United States (Active)
Researchers
- Principal investigator: Gupta, Nishant — University of Cincinnati
- Study coordinator: Gupta, Nishant
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.