Investigating how menopause affects the risk of Alzheimer's disease in women
Health of the Cholinergic System and Risk for Alzheimer's Disease in Postmenopausal Women
This study is looking at how menopause might affect women's brain health and their chances of developing Alzheimer's disease, hoping to find out how hormonal changes during this time could influence memory and thinking skills.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Vermont & St Agric College NIH-funded |
| Lab location | 1 site (Burlington, United States) |
| Project ID | NIH-10624342 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between menopause and the risk of developing Alzheimer's disease (AD) in women. It aims to explore how hormonal changes during menopause may influence cognitive function and the cholinergic system, which is critical for memory and learning. By examining these neurobiological factors, the study seeks to identify individual differences in cognitive aging and their connection to late-life risks for Alzheimer's. The findings could provide insights into how menopause-related changes may impact long-term cognitive health.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women who may be experiencing cognitive changes.
Not a fit: Patients who are not postmenopausal or those who do not have concerns about cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for assessing and managing Alzheimer's disease risk in postmenopausal women.
How similar studies have performed: Previous research has indicated a connection between hormonal changes and cognitive function, suggesting that this approach may yield valuable insights.
Where this research is happening
Burlington, United States
- University of Vermont & St Agric College — Burlington, United States (Active)
Researchers
- Principal investigator: Dumas, Julie a — University of Vermont & St Agric College
- Study coordinator: Dumas, Julie a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.