Investigating how menopause affects blood pressure and heart health in women
Official title: Aldosterone and the menopausal transition's increase in blood pressure and cardiovascular risk
Funded at University of Michigan at Ann Arbor · NIH-11091548 · Data updated 2026-11-12
This study is looking at how menopause affects blood pressure and heart health in women, especially focusing on a hormone called aldosterone, to help find ways to keep women healthier during this important time in their lives.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | May 20, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $691,380 |
| NIH project number | 5R01HL164678-02 |
| Project ID | NIH-11091548 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who are approaching or have recently experienced menopause.
✕Less likely to help
Patients who are premenopausal or have significant cardiovascular issues unrelated to menopause may not benefit from this research.
What this research studies
This research focuses on understanding the increase in blood pressure and cardiovascular risk that many women experience during the menopausal transition. It examines the role of aldosterone, a hormone involved in blood pressure regulation, and how its levels change in women around the time of menopause. By analyzing blood samples from a large group of women over several years, the study aims to identify factors that influence blood pressure changes during this critical period. The ultimate goal is to improve cardiovascular health outcomes for midlife and older women.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for hypertension in menopausal women.
How similar studies have gone: Previous research has shown that understanding hormonal changes during menopause can lead to improved management of blood pressure, indicating potential success for this approach.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Byrd, James Brian — University of Michigan at Ann Arbor
- Study coordinator: Byrd, James Brian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.