Investigating how memory lapses in older adults relate to inflammation and brain health.
Official title: Prospective Memory in Everyday Life: Lapses and Decline in Relation to Inflammatory and Neurodegenerative Biomarkers in Older Adults
Funded at University of Wyoming · NIH-10839482 · Data updated 2026-11-12
This study is looking at how well older adults remember to do things in the future, like taking their medicine or going to appointments, and how this might be connected to inflammation and brain health, while also checking if these connections are different for men and women.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wyoming NIH-funded |
| Lab location | 1 site (Laramie, United States) |
| Project start | May 15, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $158,232 |
| NIH project number | 5R03AG081565-03 |
| Project ID | NIH-10839482 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults, particularly those aged 65 and above, who may be experiencing memory lapses.
✕Less likely to help
Patients who are younger than 65 or those without any memory concerns may not benefit from this research.
What this research studies
This research focuses on prospective memory, which is the ability to remember future tasks like taking medication or attending appointments. It aims to explore how lapses in this type of memory in older adults are linked to biological markers of inflammation and neurodegeneration. By analyzing existing data from the Einstein Aging Study, the project will assess these relationships both at a single point in time and over a longer period. Additionally, the study will investigate whether these links vary based on gender or sex, providing a deeper understanding of the biological factors influencing memory decline.
Why it matters
Potential benefit: If successful, this research could lead to better identification of cognitive decline in older adults and inform interventions to support memory health.
How similar studies have gone: Previous research has shown promising results in linking cognitive decline with biological markers, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Wyoming
Laramie, United States Active
Researchers
- Principal investigator: Harrington, Erin — University of Wyoming
- Study coordinator: Harrington, Erin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.