Investigating how medications are processed and their safety in individuals with Down syndrome
CLINICAL PHARMACOKINETICS AND SAFETY TRIALS IN DOWN SYNDROME
This study is looking at how people with Down syndrome process medications to make sure they are safe and effective, so we can create better treatment options just for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10497860 on NIH RePORTER |
What this research studies
This research focuses on understanding how individuals with Down syndrome metabolize medications and the safety of these drugs for this population. It aims to identify any unique pharmacokinetic profiles that may affect drug efficacy and safety. By conducting clinical trials, the research will gather data on how these individuals respond to various medications, which can help tailor treatments specifically for them. The study will involve monitoring participants for side effects and overall health outcomes during the trial period.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with Down syndrome.
Not a fit: Patients without Down syndrome or those under the age of 21 may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective medication regimens for individuals with Down syndrome.
How similar studies have performed: Previous research has shown that understanding pharmacokinetics in specific populations can lead to significant improvements in treatment outcomes, suggesting this approach has potential for success.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Becker, Mara — Duke University
- Study coordinator: Becker, Mara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.