Investigating how medications are processed and their safety in individuals with Down syndrome
CLINICAL PHARMACOKINETICS AND SAFETY TRIALS IN DOWN SYNDROME
This study is looking at how different medications work in people with Down syndrome to make sure they are safe and effective, so we can find the best treatments for their unique needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10274297 on NIH RePORTER |
What this research studies
This research focuses on understanding the pharmacokinetics, or how drugs are absorbed, distributed, metabolized, and excreted in individuals with Down syndrome. It aims to assess the safety and effectiveness of various medications specifically for this population, who may have unique responses to drugs due to their genetic and physiological characteristics. By conducting clinical trials, the research will gather data that can help tailor medication regimens for better health outcomes in people with Down syndrome. Participants will be monitored closely to ensure their safety and to evaluate how well the medications work for them.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with Down syndrome.
Not a fit: Patients without Down syndrome or those under the age of 21 may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective medication treatments for individuals with Down syndrome.
How similar studies have performed: Previous research has shown promising results in understanding drug responses in similar populations, indicating potential for success in this area.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Becker, Mara — Duke University
- Study coordinator: Becker, Mara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.