Investigating how maternal vitamin D levels affect childhood asthma
Using statistical network methods to elucidate the multi-omic modulators of the effect of maternal vitamin D levels on childhood asthma
This study is looking at how a mother's vitamin D levels during pregnancy might affect whether her child develops asthma, and it’s for parents who want to understand how vitamin D could help their kids breathe better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10991688 on NIH RePORTER |
What this research studies
This research explores the relationship between maternal vitamin D levels during pregnancy and the development of asthma in children. It aims to identify the biological mechanisms that influence how vitamin D supplementation can prevent asthma in offspring. By analyzing genetic and epigenetic factors, the study seeks to understand why some children benefit from maternal vitamin D while others do not. The research employs advanced statistical network methods and multi-omic approaches to uncover these complex interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women who are considering or currently taking vitamin D supplements.
Not a fit: Patients who are not pregnant or those whose asthma is unrelated to prenatal factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that prevent asthma in children based on maternal vitamin D levels.
How similar studies have performed: Previous studies have shown promising results regarding the role of maternal vitamin D in preventing childhood asthma, but this research aims to provide deeper insights into the underlying mechanisms.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Halu, Arda — Brigham and Women's Hospital
- Study coordinator: Halu, Arda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.