Investigating how maternal vitamin D levels affect childhood asthma
Official title: Using statistical network methods to elucidate the multi-omic modulators of the effect of maternal vitamin D levels on childhood asthma
Funded at Brigham and Women's Hospital · NIH-10991688 · Data updated 2026-11-12
This study is looking at how a mother's vitamin D levels during pregnancy might affect whether her child develops asthma, and it’s for parents who want to understand how vitamin D could help their kids breathe better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $805,344 |
| NIH project number | 5R01HL171141-02 |
| Project ID | NIH-10991688 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women who are considering or currently taking vitamin D supplements.
✕Less likely to help
Patients who are not pregnant or those whose asthma is unrelated to prenatal factors may not benefit from this research.
What this research studies
This research explores the relationship between maternal vitamin D levels during pregnancy and the development of asthma in children. It aims to identify the biological mechanisms that influence how vitamin D supplementation can prevent asthma in offspring. By analyzing genetic and epigenetic factors, the study seeks to understand why some children benefit from maternal vitamin D while others do not. The research employs advanced statistical network methods and multi-omic approaches to uncover these complex interactions.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that prevent asthma in children based on maternal vitamin D levels.
How similar studies have gone: Previous studies have shown promising results regarding the role of maternal vitamin D in preventing childhood asthma, but this research aims to provide deeper insights into the underlying mechanisms.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Halu, Arda — Brigham and Women's Hospital
- Study coordinator: Halu, Arda
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.