Investigating how maternal health during pregnancy affects the heart health of their children.

Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH)

NIH-funded research Lurie Children's Hospital of Chicago · NIH-11047566

This study is looking at how a mother's high blood sugar during pregnancy might affect her child's heart health as they grow up, and it's for young adults who want to understand their own health better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLurie Children's Hospital of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11047566 on NIH RePORTER

What this research studies

This research focuses on understanding how maternal conditions, such as high blood sugar during pregnancy, impact the cardiovascular health of their children as they grow into young adults. By studying a large group of offspring from a previous study, researchers will assess various health indicators like blood pressure, body fat, and blood sugar levels. The goal is to identify the connections between maternal health factors and the cardiovascular risks faced by their children, potentially leading to better prevention strategies. Participants will undergo comprehensive health assessments to gather data on their cardiovascular health.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults aged 18-25 who were born to mothers with gestational diabetes or other related conditions.

Not a fit: Patients who are older than 25 or those who do not have a history of maternal gestational health issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cardiovascular disease in children whose mothers experienced gestational health issues.

How similar studies have performed: Previous studies have shown promising results in understanding the links between maternal health and offspring cardiovascular outcomes, indicating that this approach has potential for success.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.