Investigating how malaria parasites are transmitted from humans to mosquitoes
Once bitten: A longitudinal, observational study of successful malaria parasite transmission events between humans and mosquitos
This study is looking at how malaria spreads from people to mosquitoes in sub-Saharan Africa, so we can find out which infected individuals are more likely to pass the disease on and help create better ways to stop malaria from spreading.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10655429 on NIH RePORTER |
What this research studies
This research focuses on understanding the transmission of malaria parasites from humans to mosquitoes in sub-Saharan Africa. By observing natural conditions, the study aims to identify which infected individuals are most likely to pass the malaria parasites to mosquitoes, thereby contributing to the ongoing cycle of malaria transmission. The research employs a longitudinal approach, tracking specific human populations over time to identify risk factors associated with higher transmission rates. This information will help in targeting interventions more effectively to reduce malaria spread.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in sub-Saharan Africa who are at risk of malaria infection and may contribute to the transmission cycle.
Not a fit: Patients who are not residing in sub-Saharan Africa or those who are not at risk of malaria infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective malaria control strategies, ultimately reducing the incidence of malaria in affected populations.
How similar studies have performed: Other research has shown success in identifying high transmitters of malaria, indicating that this approach has potential for significant impact.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Prudhommeomeara, Wendy — Duke University
- Study coordinator: Prudhommeomeara, Wendy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.