Investigating how Lyme disease bacteria adapt to their hosts
Functional and Mechanistic Studies of the Role of Lp17-encoded Factors in Host Adaptation by the Lyme Disease Spirochete
This study is looking at how the bacteria that cause Lyme disease change and survive in different hosts, including people, to help us understand how the disease develops and lasts in patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington State University NIH-funded |
| Lab location | 1 site (Pullman, United States) |
| Project ID | NIH-10792282 on NIH RePORTER |
What this research studies
This research focuses on understanding how the Lyme disease-causing bacteria, Borrelia burgdorferi, adapt to different hosts, including humans. The team will explore specific genetic factors that influence the bacteria's ability to survive and thrive in various environments. By examining the role of certain genes and their expression, the research aims to uncover mechanisms that allow the bacteria to effectively establish infections. This could lead to insights into how Lyme disease develops and persists in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with Lyme disease or are at risk of infection.
Not a fit: Patients who do not have Lyme disease or are not at risk of exposure to ticks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating Lyme disease.
How similar studies have performed: Previous research has shown promising results in understanding bacterial adaptation mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Pullman, United States
- Washington State University — Pullman, United States (Active)
Researchers
- Principal investigator: Bankhead, Troy Michael — Washington State University
- Study coordinator: Bankhead, Troy Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.