NIH-funded research R03 grant

Investigating how low potassium levels cause kidney injury

Official title: Establishing new model systems to study low potassium induced kidney injury

Funded at University of Pittsburgh at Pittsburgh · NIH-11013316 · Data updated 2026-11-12

This study is looking at how not getting enough potassium in your diet can harm your kidneys and lead to high blood pressure, and it aims to find out more about how this happens so we can help people with kidney problems.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startJanuary 25, 2024
Project endDecember 31, 2025
Funding year2025
Award (this year)$104,936
NIH project number5R03DK138215-02
Project IDNIH-11013316 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with a history of dietary potassium deficiency or related kidney issues.

Less likely to help

Patients with normal potassium levels and no kidney-related health concerns may not benefit from this research.

What this research studies

This research focuses on understanding the effects of dietary potassium deficiency on kidney health. By developing new cellular models, the study aims to explore how low potassium levels lead to kidney injury, hypertension, and other related health issues. The researchers will examine the mechanisms involved, including inflammation and changes in kidney function, to better understand the connection between potassium levels and kidney damage. This work could provide insights into potential treatments for patients suffering from kidney-related conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and treating kidney injury related to low potassium levels.

How similar studies have gone: While the specific approach of this research is novel, previous studies have indicated that understanding potassium's role in kidney health is crucial and has shown promising results.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Boyd-Shiwarski, Cary Ragan — University of Pittsburgh at Pittsburgh
  • Study coordinator: Boyd-Shiwarski, Cary Ragan

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.