Investigating how low blood sugar affects brain health in diabetes
Cerebral ischemia and exposure to recurrent hypoglycemia in diabetes
This study is looking at how repeated low blood sugar episodes might affect the brain health of people with diabetes and increase their risk of having a stroke, with the hope of finding better ways to help manage their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10877849 on NIH RePORTER |
What this research studies
This research aims to enhance the neurological health of individuals with diabetes by exploring the relationship between recurrent low blood sugar episodes and the risk of stroke. The study uses an animal model to assess how prior exposure to low blood sugar influences the severity of cerebral ischemia, a condition that can lead to strokes. By examining the underlying mechanisms, the research seeks to identify how these episodes may worsen brain damage during ischemic events. The findings could lead to better management strategies for diabetes patients at risk of stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with type 1 or type 2 diabetes who experience recurrent episodes of low blood sugar.
Not a fit: Patients who do not have diabetes or do not experience hypoglycemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols that reduce the risk of stroke in diabetes patients.
How similar studies have performed: Previous studies have shown that managing blood sugar levels can significantly impact the complications associated with diabetes, suggesting that this research builds on established findings.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Dave, Kunjan R — University of Miami School of Medicine
- Study coordinator: Dave, Kunjan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.