Investigating how living in different neighborhoods affects the risk of Alzheimer's disease in diverse older adults
Official title: Lifecourse Residential Segregation, Ethnic Enclaves and Risk and Resilience to ADRD in Diverse Cohorts
Funded at University of California at Davis · NIH-10993105 · Data updated 2026-11-12
This study is looking at how where you live might affect the chances of getting Alzheimer's disease and related dementia, especially for older Black and Hispanic/Latinx adults, to see if living in neighborhoods with people from the same background helps or hurts brain health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $41,826 |
| NIH project number | 5F31AG085937-02 |
| Project ID | NIH-10993105 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults aged 65 and above, particularly those from Black and Hispanic/Latinx communities living in Northern California.
✕Less likely to help
Patients who are younger than 65 or those not residing in the targeted geographic area may not benefit from this research.
What this research studies
This research examines the impact of residential segregation on the risk of Alzheimer's disease and related dementia (ADRD) among older adults, particularly focusing on Black and Hispanic/Latinx populations. It aims to understand how living in ethnic enclaves may either increase or decrease the risk of cognitive decline and ADRD. By analyzing data from two longitudinal studies, the project will assess various factors such as education and poverty rates that may influence this relationship. Participants will undergo cognitive assessments and neuroimaging to gather comprehensive data on brain health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of how neighborhood environments affect cognitive health, potentially informing public health strategies to reduce ADRD risk.
How similar studies have gone: Previous studies have shown mixed results regarding the effects of residential segregation on cognitive decline, indicating that this research could provide novel insights into this complex relationship.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Lor, Yi — University of California at Davis
- Study coordinator: Lor, Yi
Related research
Other NIH-funded projects on the same topics.
-
Cognitive SuperAging: Exploring why some octogenarians stay sharp in memory
This NIH grant studies why a small group of people aged 80+ keep memory skills as good as much younger people, hoping to understand how to protect memory as we age.
-
National Neighborhood Data Archive helps researchers study aging health in U.S. neighborhoods
A nationwide data resource will help researchers understand how where people live affects health and aging, with a focus on respiratory illnesses in older adults.
-
Understanding how neurons resist and recover from toxic chemicals
Researchers are studying how brain cells fight back against harmful chemicals to help people survive exposure.
-
Fostering Community Connections to Strengthen Youth Resilience and Well-Being
A Hawaii-based effort helps teens and young adults get mental health and preventive care more easily by building local networks and smart referral pathways.
-
Indigenous healthy homes and communities to improve health and resilience
A community-led effort in Indigenous communities in the US Southwest aims to improve housing and health, focusing on safer homes, cleaner indoor environments, and access to culturally competent care.
-
Neural Circuitry Resilience in Psychotic Disorders
Researchers are using ultra-high-field brain scans to understand how brain networks in people with schizophrenia adapt over time, with the goal of finding new ways to improve thinking and daily functioning.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.