Investigating how liver fat and fibrosis affect heart disease risk.
Role of liver fat and fibrosis in human CVD risk phenotypes.
['FUNDING_P01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10908536
This study is looking at how extra fat in the liver and liver scarring might affect heart health in people with nonalcoholic fatty liver disease, using special imaging to measure these factors and help find better ways to prevent and treat heart problems.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10908536 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the relationship between liver fat, liver fibrosis, and cardiovascular disease (CVD) risk, particularly in individuals with nonalcoholic fatty liver disease (NAFLD). By using advanced non-invasive imaging techniques, the study aims to quantify liver fat and fibrosis in participants, assessing their cardiovascular risk profiles through established scoring systems. The goal is to uncover the mechanisms linking liver health to heart disease, which could lead to better prevention and treatment strategies for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with nonalcoholic fatty liver disease (NAFLD) or those at risk for cardiovascular disease.
Not a fit: Patients without liver disease or those who do not have risk factors for cardiovascular disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for assessing and managing cardiovascular risk in patients with liver disease.
How similar studies have performed: Previous research has shown promising results in using non-invasive imaging techniques to assess liver conditions and their impact on cardiovascular health, indicating that this approach has potential for success.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LOOMBA, ROHIT — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: LOOMBA, ROHIT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiovascular Diseases