Investigating how lipid signaling affects aging cells and lung health
Lipid signaling in cellular senescence and tissue aging
['FUNDING_R01'] · UNIVERSITY OF CHICAGO · NIH-10906921
This study is looking at how certain changes in fat-related processes in the body and aging cells might affect idiopathic pulmonary fibrosis, with the hope of finding new ways to help slow down the disease for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10906921 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding idiopathic pulmonary fibrosis, a serious lung disease that currently lacks effective treatments. It examines how changes in lipid signaling and metabolism, particularly involving senescent cells, contribute to the disease's progression. By analyzing the interactions between lipid pathways and cellular aging, the research aims to identify potential strategies to prevent or slow down the disease. Patients may benefit from insights that could lead to new therapeutic approaches targeting these cellular processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis or those experiencing related lung health issues.
Not a fit: Patients with other forms of lung disease unrelated to idiopathic pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent or slow the progression of idiopathic pulmonary fibrosis.
How similar studies have performed: Previous research has shown promising results in targeting lipid signaling pathways in other diseases, suggesting potential for success in this area as well.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KRON, STEPHEN J. — UNIVERSITY OF CHICAGO
- Study coordinator: KRON, STEPHEN J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.