Investigating how light therapy affects brain changes in people with mild cognitive impairment and mild Alzheimer's Disease
Use of 7T multimodal imaging to detect brain changes associated with light therapy in persons with mild cognitive impairment and mild Alzheimer's Disease
['FUNDING_R21'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10673010
This study is looking at how a special lighting therapy can help improve sleep and thinking skills in older adults who have mild cognitive issues or early Alzheimer's, using advanced brain imaging to see how it works.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10673010 on ClinicalTrials.gov |
What this research studies
This research explores the effects of a specialized lighting intervention therapy (LIT) on sleep and cognitive function in older adults with mild cognitive impairment and mild Alzheimer's Disease. Using advanced 7T multimodal imaging, the study aims to detect changes in brain structure and function associated with improved sleep quality. Participants will undergo high-resolution imaging to identify how LIT influences key brain regions involved in memory and cognition. The goal is to better understand the mechanisms behind LIT's benefits and its potential to enhance overall well-being in these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults diagnosed with mild cognitive impairment or mild Alzheimer's Disease who experience poor sleep.
Not a fit: Patients with severe Alzheimer's Disease or other advanced neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved sleep and cognitive function for patients with mild cognitive impairment and mild Alzheimer's Disease.
How similar studies have performed: Previous research has shown promising results with light therapy in improving sleep and cognitive outcomes in similar patient populations, suggesting a potential for success in this approach.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BALCHANDANI, PRITI — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: BALCHANDANI, PRITI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.