Investigating how life changes affect suicide risk

Aging, Major Life Transitions, and Suicide Risk

['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10983321

This study looks at how big life changes, like moving, changing jobs, or shifts in friendships, can affect the risk of suicide at different ages, and it aims to find ways to help prevent this risk by understanding what factors might make it better or worse.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-10983321 on ClinicalTrials.gov

What this research studies

This research examines the relationship between major life transitions, such as changes in social relationships, health, work, and residence, and suicide risk behaviors across different stages of life. By analyzing existing datasets from two longitudinal studies, the research aims to identify factors that may increase or decrease the risk of suicide. It will also explore how individual characteristics, like age and mental health history, and contextual factors, such as neighborhood conditions, influence this relationship. The goal is to uncover modifiable risk factors that can inform public health strategies for suicide prevention.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults experiencing significant life transitions, particularly those aged 25 and older.

Not a fit: Patients who are not experiencing major life transitions or who are under 25 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies that reduce suicide risk among vulnerable populations.

How similar studies have performed: Previous research has shown success in identifying risk factors for suicide using similar longitudinal approaches, indicating the potential for impactful findings in this study.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.