Investigating how Kisspeptin affects metabolism during pregnancy
Official title: The Role of Kisspeptin in Metabolism Regulation
Funded at University of California-Irvine · NIH-11076743 · Data updated 2026-11-12
This study is looking at how a hormone called Kisspeptin, made by the placenta, helps manage sugar levels and energy during pregnancy, which is important for keeping both moms and their babies healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | April 18, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $445,553 |
| NIH project number | 5R01DK134342-02 |
| Project ID | NIH-11076743 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant women, particularly those in the third trimester, who may be experiencing metabolic challenges.
✕Less likely to help
Patients who are not pregnant or those who are not in the specified age range (0-11 years) may not receive benefits from this research.
What this research studies
This research explores the role of Kisspeptin, a hormone produced by the placenta, in regulating metabolism during pregnancy. It aims to understand how Kisspeptin influences maternal glucose levels and overall metabolic adaptations necessary for the health of both the mother and the developing fetus. The study will involve examining the mechanisms by which Kisspeptin interacts with liver cells to manage energy balance and nutrient supply. By analyzing these processes, the research seeks to uncover critical insights that could improve maternal and fetal health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better management of metabolic health during pregnancy, potentially reducing risks for both mothers and their babies.
How similar studies have gone: While some research has explored the role of hormones in pregnancy, the specific focus on Kisspeptin's metabolic effects is relatively novel and has not been extensively tested.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Hussain, Mehboob a — University of California-Irvine
- Study coordinator: Hussain, Mehboob a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.