Investigating how Kisspeptin affects metabolism during pregnancy
The Role of Kisspeptin in Metabolism Regulation
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-11076743
This study is looking at how a hormone called Kisspeptin, made by the placenta, helps manage sugar levels and energy during pregnancy, which is important for keeping both moms and their babies healthy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-11076743 on ClinicalTrials.gov |
What this research studies
This research explores the role of Kisspeptin, a hormone produced by the placenta, in regulating metabolism during pregnancy. It aims to understand how Kisspeptin influences maternal glucose levels and overall metabolic adaptations necessary for the health of both the mother and the developing fetus. The study will involve examining the mechanisms by which Kisspeptin interacts with liver cells to manage energy balance and nutrient supply. By analyzing these processes, the research seeks to uncover critical insights that could improve maternal and fetal health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women, particularly those in the third trimester, who may be experiencing metabolic challenges.
Not a fit: Patients who are not pregnant or those who are not in the specified age range (0-11 years) may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of metabolic health during pregnancy, potentially reducing risks for both mothers and their babies.
How similar studies have performed: While some research has explored the role of hormones in pregnancy, the specific focus on Kisspeptin's metabolic effects is relatively novel and has not been extensively tested.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUSSAIN, MEHBOOB A — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: HUSSAIN, MEHBOOB A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.