Investigating how kidney nerves affect blood pressure regulation
Renal Afferent Nerve Circuitry and Pathogenesis on Blood Pressure Regulation
This study is looking at how certain nerves in the kidneys help control blood pressure, especially when it gets too high due to salt, and it aims to find new ways to treat high blood pressure that could help people like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10900242 on NIH RePORTER |
What this research studies
This research explores the role of sensory afferent renal nerves in regulating blood pressure and their potential contribution to neurogenic hypertension. By using advanced techniques like viral vector-based neurotracing, the study aims to identify the pathways through which these nerves communicate with central autonomic regions in the brain. The research will focus on understanding how these renal nerves influence blood pressure control, particularly in a model of salt-induced hypertension. Patients may benefit from insights that could lead to new treatments for hypertension and related cardiometabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from hypertension, particularly those with neurogenic hypertension.
Not a fit: Patients with normal blood pressure or those not affected by hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for hypertension and reduce the risk of related health issues.
How similar studies have performed: Previous research has shown promising results in understanding the role of renal nerves in blood pressure regulation, suggesting that this approach could lead to significant advancements.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Dailey-Krempel, Brianna — University of Minnesota
- Study coordinator: Dailey-Krempel, Brianna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.