Investigating how kidney nerves affect blood pressure regulation
Official title: Renal Afferent Nerve Circuitry and Pathogenesis on Blood Pressure Regulation
Funded at University of Minnesota · NIH-10900242 · Data updated 2026-11-12
This study is looking at how certain nerves in the kidneys help control blood pressure, especially when it gets too high due to salt, and it aims to find new ways to treat high blood pressure that could help people like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 3, 2024 |
| Project end | September 2, 2027 |
| Funding year | 2024 |
| Award (this year) | $38,538 |
| NIH project number | 1F31DK139599-01 |
| Project ID | NIH-10900242 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from hypertension, particularly those with neurogenic hypertension.
✕Less likely to help
Patients with normal blood pressure or those not affected by hypertension may not benefit from this research.
What this research studies
This research explores the role of sensory afferent renal nerves in regulating blood pressure and their potential contribution to neurogenic hypertension. By using advanced techniques like viral vector-based neurotracing, the study aims to identify the pathways through which these nerves communicate with central autonomic regions in the brain. The research will focus on understanding how these renal nerves influence blood pressure control, particularly in a model of salt-induced hypertension. Patients may benefit from insights that could lead to new treatments for hypertension and related cardiometabolic diseases.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for hypertension and reduce the risk of related health issues.
How similar studies have gone: Previous research has shown promising results in understanding the role of renal nerves in blood pressure regulation, suggesting that this approach could lead to significant advancements.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Dailey-Krempel, Brianna — University of Minnesota
- Study coordinator: Dailey-Krempel, Brianna
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.