Investigating how kidney injury affects lung health
Official title: Remote injury responses after AKI
Funded at St. Louis VA Medical Center · NIH-10911017 · Data updated 2026-11-12
This study is looking at how kidney problems can affect the lungs and aims to find out what happens in the body during this process, so we can discover new ways to help patients who experience lung issues after kidney injury.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Louis VA Medical Center NIH-funded |
| Lab location | 1 site (St. Louis, UNITED STATES) |
| Project start | July 1, 2021 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| NIH project number | 5I01BX005322-04 |
| Project ID | NIH-10911017 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced acute kidney injury and are at risk for developing lung complications.
✕Less likely to help
Patients with chronic lung conditions unrelated to acute kidney injury may not benefit from this research.
What this research studies
This research focuses on understanding the complications that arise in the lungs following acute kidney injury (AKI). It aims to identify the molecular mechanisms involved, particularly the role of inflammatory cytokines and immune cells in this process. By studying how specific kidney cells influence lung responses, the research seeks to uncover potential therapeutic targets for treating remote lung injuries caused by AKI. Patients may benefit from insights that could lead to new treatments for these serious complications.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for preventing or treating lung injuries that occur as a result of kidney damage.
How similar studies have gone: While the specific approach of this research is novel, previous studies have indicated that understanding the immune response in related conditions can lead to significant advancements in treatment.
Where this research is happening
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St. Louis VA Medical Center
St. Louis, United States Active
Researchers
- Principal investigator: Herrlich, Andreas — St. Louis VA Medical Center
- Study coordinator: Herrlich, Andreas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.