Investigating how kHz spinal cord stimulation affects temperature and pain control

kHz frequency Spinal Cord Stimulation: Novel Temperature-Based Mechanisms of Action

NIH-funded research City College of New York · NIH-10842371

This study is looking at how a special type of spinal cord stimulation can help manage pain by possibly warming up the tissue in your body, and it aims to find out if this warming effect can improve pain relief for patients like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCity College of New York NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10842371 on NIH RePORTER

What this research studies

This research explores the mechanisms behind kHz spinal cord stimulation (SCS) and its potential to manage pain. The team will develop advanced tools to model how this stimulation affects tissue temperature, which may play a crucial role in its effectiveness. By using a combination of computer modeling and testing in a swine model, the researchers aim to determine if kHz SCS can raise tissue temperature by 0.5-2 degrees Celsius, which could lead to new insights into pain management techniques. Patients may benefit from a better understanding of how this technology works and its implications for pain relief.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from chronic pain who may benefit from spinal cord stimulation therapies.

Not a fit: Patients who do not experience chronic pain or those who are not candidates for spinal cord stimulation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for patients using spinal cord stimulation.

How similar studies have performed: While spinal cord stimulation is a well-established treatment, the specific mechanisms of kHz SCS are still being explored, making this research both innovative and necessary.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.