Investigating how ketogenic diets and exercise can improve brain health and metabolism as we age
Ketogenic oscillations and neurometabolic healthspan
This study is looking at how following a ketogenic diet and exercising can help older adults improve their brain health and overall well-being, by switching between using carbs and fats for energy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10849833 on NIH RePORTER |
What this research studies
This research explores the effects of ketogenic diets and exercise on metabolic health and cognitive function in aging individuals. It focuses on how alternating between carbohydrate and fat utilization can enhance brain health and overall physical well-being. By examining the role of ketone metabolism, the study aims to understand how dietary and exercise interventions can mitigate cognitive decline and improve healthspan. Participants may engage in dietary changes and exercise regimens to assess their impact on metabolism and cognition.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing cognitive decline or those interested in improving their metabolic health through dietary and exercise interventions.
Not a fit: Patients with severe cognitive impairment or those unable to participate in dietary changes or exercise may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary and exercise strategies that significantly improve cognitive function and metabolic health in older adults.
How similar studies have performed: Previous research has shown promising results with ketogenic diets in improving cognitive function and metabolic health, indicating that this approach may be effective.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Crawford, Peter a — University of Minnesota
- Study coordinator: Crawford, Peter a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.