Investigating how ketamine affects depression and brain changes in Veterans with Parkinson's disease
Examining ketamine effects on depression, neuroplasticity, and inflammation in Veterans with Parkinson's disease
This study is looking at how ketamine might help improve mood and brain flexibility in Veterans with Parkinson's disease who are dealing with depression, and it aims to find better ways to treat their symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10798850 on NIH RePORTER |
What this research studies
This research explores the effects of ketamine on depression and neuroplasticity in Veterans suffering from Parkinson's disease. It aims to understand how ketamine may improve depressive symptoms by targeting inflammation and enhancing brain adaptability. The study will involve assessing the relationship between neuroplasticity, inflammation, and depression in this population, utilizing advanced methodologies to measure brain activity and mood changes. By focusing on these interconnected factors, the research seeks to develop more effective treatments for depression in Parkinson's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are Veterans diagnosed with Parkinson's disease who also suffer from depression.
Not a fit: Patients without a diagnosis of Parkinson's disease or those not experiencing depressive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for Veterans with Parkinson's disease who experience depression.
How similar studies have performed: Previous research has shown promising results in using ketamine for treating depression, suggesting potential for success in this novel application.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Bradley, Ellen R — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Bradley, Ellen R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.