Investigating how insulin resistance may lead to Alzheimer's disease
Exploring Common Biological Pathways Underlying Insulin Resistance and Alzheimer Disease using Genetic and Omic Tools
This study is looking at how insulin resistance might be connected to Alzheimer's disease, with the hope of finding new ways to prevent or treat Alzheimer's that could help people stay healthier for longer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10893645 on NIH RePORTER |
What this research studies
This research explores the connection between insulin resistance (IR) and Alzheimer's disease (AD) to understand how IR may contribute to the development of AD. By utilizing advanced genetic and omic tools, the study aims to identify the biological pathways that link these two conditions. Patients may benefit from insights that could lead to new preventive or therapeutic strategies targeting insulin sensitivity, potentially delaying or preventing the onset of Alzheimer's disease. The research is led by Dr. Chloé Sarnowski, who focuses on genetic and environmental risk factors associated with complex traits.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with insulin resistance or related metabolic conditions.
Not a fit: Patients who do not have insulin resistance or are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve insulin sensitivity and help prevent or delay Alzheimer's disease.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between insulin resistance and Alzheimer's disease, suggesting that this approach may yield valuable insights.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Sarnowski, Chloé — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Sarnowski, Chloé
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.