Investigating how insomnia treatment affects Crohn’s disease
Official title: A Fully Remote Pilot Randomized Controlled Trial to Investigate the Impact of Insomnia Treatment on Crohn’s disease
Funded at Dartmouth-Hitchcock Clinic · NIH-10992134 · Data updated 2026-11-12
This study is looking at how helping people with Crohn's disease sleep better can make their symptoms and overall well-being improve, using a special therapy designed for insomnia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth-Hitchcock Clinic NIH-funded |
| Lab location | 1 site (Lebanon, United States) |
| Project start | February 15, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $188,024 |
| NIH project number | 5K23DK134814-03 |
| Project ID | NIH-10992134 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with Crohn’s disease and are experiencing insomnia.
✕Less likely to help
Patients who do not have Crohn’s disease or who do not experience insomnia may not benefit from this research.
What this research studies
This research explores the relationship between insomnia and Crohn’s disease, focusing on how treating insomnia can improve symptoms and quality of life for patients. It involves a pilot randomized controlled trial using Cognitive Behavioral Therapy for Insomnia (CBT-I), specifically adapted for individuals with Crohn’s disease. Participants will be monitored for changes in sleep patterns, Crohn’s symptoms, and inflammation levels, with a mixed-methods approach to assess the treatment's feasibility and acceptability.
Why it matters
Potential benefit: If successful, this research could lead to improved management of Crohn’s disease symptoms and overall quality of life for patients suffering from insomnia.
How similar studies have gone: Previous research has shown that Cognitive Behavioral Therapy for Insomnia is effective in other populations, suggesting potential for success in this novel application for Crohn’s disease patients.
Where this research is happening
-
Dartmouth-Hitchcock Clinic
Lebanon, United States Active
Researchers
- Principal investigator: Salwen-Deremer, Jessica K — Dartmouth-Hitchcock Clinic
- Study coordinator: Salwen-Deremer, Jessica K
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Cognitive-Behavioral Therapy and Trazodone for Sleep and Blood Pressure in Insomnia Subtypes
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.