Investigating how insomnia treatment affects Crohn’s disease

A Fully Remote Pilot Randomized Controlled Trial to Investigate the Impact of Insomnia Treatment on Crohn’s disease

NIH-funded research Dartmouth-Hitchcock Clinic · NIH-10992134

This study is looking at how helping people with Crohn's disease sleep better can make their symptoms and overall well-being improve, using a special therapy designed for insomnia.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDartmouth-Hitchcock Clinic NIH-funded
Lab location1 site (Lebanon, United States)
Project IDNIH-10992134 on NIH RePORTER

What this research studies

This research explores the relationship between insomnia and Crohn’s disease, focusing on how treating insomnia can improve symptoms and quality of life for patients. It involves a pilot randomized controlled trial using Cognitive Behavioral Therapy for Insomnia (CBT-I), specifically adapted for individuals with Crohn’s disease. Participants will be monitored for changes in sleep patterns, Crohn’s symptoms, and inflammation levels, with a mixed-methods approach to assess the treatment's feasibility and acceptability.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with Crohn’s disease and are experiencing insomnia.

Not a fit: Patients who do not have Crohn’s disease or who do not experience insomnia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management of Crohn’s disease symptoms and overall quality of life for patients suffering from insomnia.

How similar studies have performed: Previous research has shown that Cognitive Behavioral Therapy for Insomnia is effective in other populations, suggesting potential for success in this novel application for Crohn’s disease patients.

Where this research is happening

Lebanon, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.