Investigating how inflammation resolution can prevent cardiovascular disease
Targeting the Active Resolution of Inflammation for Cardiovascular Disease Prevention
This study is looking at how inflammation affects heart disease and whether certain natural substances in the body can help reduce that inflammation to keep your heart healthy, and we’d love for patients to help by sharing samples or information.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10989910 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of inflammation in cardiovascular disease (CVD) and how actively resolving inflammation can help prevent it. The study will explore specific chemical mediators known as specialized pro-resolving mediators (SPMs) that play a crucial role in the resolution of inflammation. By analyzing plasma levels of these mediators in relation to CVD risk, the research aims to identify which SPMs may provide protective benefits against heart disease. Patients may be involved in providing samples or data to help uncover these important connections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for cardiovascular disease, particularly those with chronic inflammation or related health conditions.
Not a fit: Patients who are not at risk for cardiovascular disease or do not have inflammatory conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cardiovascular disease by targeting inflammation more effectively.
How similar studies have performed: Previous research has shown promising results in targeting inflammation to reduce cardiovascular events, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Mora, Samia — Brigham and Women's Hospital
- Study coordinator: Mora, Samia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.