Investigating how inflammation contributes to early prostate lesions and cancer development
Elucidating and testing causal drivers of inflammation triggered prostatic early lesions
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10918239
This study is looking at how inflammation in the early stages of prostate issues might lead to prostate cancer, and it's for anyone interested in understanding how inflammation could affect their prostate health and cancer risk.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10918239 on ClinicalTrials.gov |
What this research studies
This research explores the role of inflammation in the early stages of prostate lesions, specifically how inflammatory responses may lead to the initiation of prostate cancer. The team is examining the presence of inflammatory cells in prostate tissue and their potential to influence cancer progression. By analyzing gene expression changes in these cells, the researchers aim to identify key molecular mechanisms that could be targeted for prevention or treatment. Patients may benefit from insights into how inflammation affects their prostate health and cancer risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include men with early-stage prostate lesions or those at high risk for prostate cancer due to inflammatory conditions.
Not a fit: Patients with advanced prostate cancer or those without any signs of prostate lesions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating prostate cancer by targeting inflammatory processes.
How similar studies have performed: Previous research has shown that targeting inflammatory pathways can be effective in cancer prevention, suggesting that this approach may yield promising results.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DE MARZO, ANGELO MICHAEL — JOHNS HOPKINS UNIVERSITY
- Study coordinator: DE MARZO, ANGELO MICHAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers