Investigating how inflammation affects heart failure in women
HFpEF Susceptibility in Women: The Role of Inflammation
This study is looking at how inflammation affects heart failure with preserved ejection fraction (HFpEF) in women, aiming to find new ways to help those at risk by understanding the connection between inflammation and heart health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11075843 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of inflammation in heart failure with preserved ejection fraction (HFpEF), particularly in women. It aims to explore how systemic inflammation contributes to the higher prevalence of HFpEF in females compared to males. By analyzing eicosanoids, which are bioactive lipids involved in the inflammatory response, the study seeks to identify potential therapeutic targets and improve treatment options for women at risk of HFpEF. Patients may be involved in assessments that help clarify the relationship between inflammation and heart health.
Who could benefit from this research
Good fit: Ideal candidates for this research are women, particularly those who are post-menopausal and at risk for heart failure.
Not a fit: Patients who are not female or who do not have heart failure with preserved ejection fraction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for women suffering from heart failure.
How similar studies have performed: Previous research has indicated that understanding inflammation can lead to significant advancements in treating heart failure, suggesting a promising avenue for this investigation.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Lau, Emily — Massachusetts General Hospital
- Study coordinator: Lau, Emily
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.