Investigating how infections can trigger autoimmune responses and blood clotting issues.
Thromboinflammatory consequences of infection-induced autoimmunity
This study is looking at how infections like COVID-19 might trigger the immune system to mistakenly attack the body, which could lead to blood clotting problems, and it's for anyone interested in understanding how we can better manage these issues in people who have had infections.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11292500 on NIH RePORTER |
What this research studies
This research explores the relationship between infections, particularly COVID-19, and the development of autoimmune conditions that can lead to blood clotting disorders. It focuses on understanding how autoantibodies, which are proteins produced by the immune system that mistakenly target the body's own tissues, are generated during infections. By studying these mechanisms, the research aims to identify potential therapeutic targets that could help manage or prevent complications associated with autoimmune responses in infected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced severe COVID-19 symptoms and may be at risk for developing autoimmune disorders.
Not a fit: Patients who do not have a history of autoimmune conditions or have not been infected with COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for patients suffering from autoimmune conditions triggered by infections, improving their health outcomes.
How similar studies have performed: Previous research has shown promising results in understanding the links between infections and autoimmune responses, suggesting that this approach could yield significant insights.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Zuo, Yu — University of Michigan at Ann Arbor
- Study coordinator: Zuo, Yu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.