Investigating how improved blood sugar control affects brain glucose transport in type 2 diabetes.
Reversibility of brain glucose kinetics in type 2 diabetic subjects
This study is looking at how high blood sugar from type 2 diabetes might affect how sugar gets to your brain and if keeping your blood sugar in check can help improve brain function, so it's for people with diabetes who want to learn more about how managing their condition could benefit their thinking and memory.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11124882 on NIH RePORTER |
What this research studies
This research focuses on understanding how chronic high blood sugar levels in type 2 diabetes can impair glucose transport to the brain, potentially leading to cognitive decline. The study aims to determine if better management of blood sugar levels can reverse these effects and restore normal brain glucose metabolism. Using advanced imaging techniques, researchers will assess changes in brain function and glucose transport in patients with poorly controlled diabetes. The findings could provide insights into the relationship between diabetes management and brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with poorly controlled type 2 diabetes who are experiencing cognitive difficulties.
Not a fit: Patients with well-controlled diabetes or those without cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that protect brain function in individuals with type 2 diabetes.
How similar studies have performed: Previous studies have indicated that improving blood sugar control can have positive effects on brain health, suggesting potential success for this approach.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Sanchez Rangel, Elizabeth — Yale University
- Study coordinator: Sanchez Rangel, Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.