Investigating how immune cells target the kidneys
Official title: A new paradigm of glomerular immune cell homing
Funded at University of Southern California · NIH-10978222 · Data updated 2026-11-12
This study is looking at how immune cells move to the kidneys in people with conditions like diabetic kidney disease and lupus nephritis, with the goal of finding new ways to treat these issues and improve kidney health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | December 15, 2022 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $427,475 |
| NIH project number | 5R01DK135290-03 |
| Project ID | NIH-10978222 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with diabetic kidney disease or lupus nephritis.
✕Less likely to help
Patients with kidney diseases unrelated to immune cell activity may not benefit from this research.
What this research studies
This research explores the mechanisms by which immune cells migrate to the kidneys, particularly focusing on conditions like diabetic kidney disease and lupus nephritis. It aims to uncover how these cells interact with kidney structures and how this knowledge can lead to new treatments. The study will analyze the role of specific kidney cells in regulating immune responses and inflammation, potentially leading to repurposing existing therapies or developing new anti-inflammatory options. Patients may benefit from insights that could improve kidney disease management.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that better manage kidney diseases and reduce inflammation.
How similar studies have gone: Previous research has shown promise in understanding immune cell behavior in other contexts, suggesting potential for success in this novel approach.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Peti-Peterdi, Janos — University of Southern California
- Study coordinator: Peti-Peterdi, Janos
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.