Investigating how immune cells protect against cancer

Tissue Resident memory T cell responses to cancer

['FUNDING_R01'] · DARTMOUTH COLLEGE · NIH-10887623

This study is looking at special immune cells that help fight cancer, to learn how they work and move in the body, with the hope of finding better treatments for patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorDARTMOUTH COLLEGE (nih funded)
Locations1 site (HANOVER, UNITED STATES)
Trial IDNIH-10887623 on ClinicalTrials.gov

What this research studies

This research focuses on a specific type of immune cell known as resident memory T cells, which play a crucial role in defending the body against cancer. The study aims to understand how these cells are formed, how they move within the body, and their potential benefits for cancer treatment. By examining the mechanisms that allow these cells to thrive in tissues, particularly in lymph nodes near tumors, the research seeks to uncover new strategies for enhancing cancer immunity. Patients may benefit from insights that could lead to improved therapies targeting these immune responses.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with melanoma or other cancers who are interested in understanding their immune response.

Not a fit: Patients with non-cancerous conditions or those not diagnosed with melanoma may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that enhance the body's immune response against cancer.

How similar studies have performed: Previous research has shown promising results in understanding immune responses in cancer, suggesting that this approach could lead to significant advancements.

Where this research is happening

HANOVER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.